Table 4.
Sex stratified associations between individual symptom, symptoms combination patterns and counts on frailty
| Male | Female | |||||||
|---|---|---|---|---|---|---|---|---|
| Model 1 | P- value | Model 2 | P- value | Model 1 | P- value | Model 2 | P- value | |
| OR(95%CI) | OR(95%CI) | OR(95%CI) | OR(95%CI) | |||||
| Individual symptom | ||||||||
| Chronic pain | ||||||||
| No | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| Yes | 2.24(1.37,3.68) | 0.001 | 2.03(1.11,3.71) | 0.021 | 1.18(0.63,2.22) | 0.610 | 1.07(0.51,2.25) | 0.865 |
| Depressive symptoms | ||||||||
| No | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| Yes | 3.22(1.53,6.77) | 0.002 | 2.98(1.16,7,70) | 0.024 | 1.44(0.65,3.18) | 0.374 | 1.75(0.71,4.32) | 0.222 |
| Poor sleep quality | ||||||||
| No | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| Yes | 1.91(1.19,3.07) | 0.007 | 1.64(0.92,2.93) | 0.091 | 1.97(0.96,4.05) | 0.065 | 1.44(0.63,3.32) | 0.392 |
| symptom combination patterns | ||||||||
| No symptom | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| Chronic pain only | 2.66(1.22,5.83) | 0.014 | 2.59(1.01,6.61) | 0.047 | 0.56(0.11,2.95) | 0.496 | 0.59(0.09,3.72) | 0.571 |
| Depressive symptoms only | 2.04(0.18,23.4) | 0.567 | 1.73(0.12,25.43) | 0.689 | 2.25(0.18,27.96) | 0.528 | 1.44(0.09,22.62) | 0.797 |
| Poor sleep quality only | 1.75(0.93,3.28) | 0.081 | 1.47(0.68,3.18) | 0.325 | 1.69(0.66,4.31) | 0.274 | 1.23(0.41,3.69) | 0.712 |
| Chronic pain and depressive symptoms | 2.04(0.18,23.41) | 0.567 | 1.08(0.03,38.92) | 0.967 | - | 1.000 | - | 1.000 |
| Poor sleep quality and depressive symptoms | 5.71(1.67,19.51) | 0.005 | 6.92(1.48,32.42) | 0.014 | 2.42(0.73,8.02) | 0.147 | 2.40(0.62,9.33) | 0.207 |
| Poor sleep quality and chronic pain | 2.94(1.39,6.20) | 0.005 | 2.48(1.02,5.98) | 0.044 | 2.25(0.85,5.95) | 0.102 | 1.45(0.47,4.54) | 0.520 |
| Poor sleep quality and chronic pain and depressive symptoms | 7.34(2.26,23.84) | 0.001 | 4.50(1.08,18.73) | 0.039 | 1.93(0.41,9.13) | 0.408 | 1.76(0.29,10.72) | 0.542 |
| Symptom counts | ||||||||
| 0 | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| 1 | 1.99(1.13,3.52) | 0.018 | 1.78(0.90,3.52) | 0.097 | 1.43(0.58,3.56) | 0.439 | 1.11(0.39,3.19) | 0.849 |
| 2 | 3.32(1.68,6.53) | 0.001 | 2.90(1.29,6.52) | 0.010 | 2.25(0.90,5.62) | 0.082 | 1.68(0.58,4.87) | 0.339 |
| 3 | 7.34(2.26,23.84) | 0.001 | 4.46(1.08,18.38) | 0.039 | 1.93(0.41,9.13) | 0.408 | 1.80(0.30,10.94) | 0.525 |
Model 1: no adjusted model
Model 2: adjusting for age,marriage status, educational level, CIRS-G score, polypharmacy, time from admission to assessment and MMSE score
OR odd ratio, CI confidence interval
Significance difference P < 0.05 is shown in bold