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. 2022 Nov 2;13:950441. doi: 10.3389/fimmu.2022.950441

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Copyright © 2022 Zhang, Cai, Su, Jing, Liu, Na, Qiu, Tian, Liu, Wu, Yan and Han

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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High levels of Kyn as a prognostic indicator in STEMI patients. (A) Kaplan-Meier plots indicated the association between quartile levels of Kyn and major adverse cardiovascular events, the numbers of STEMI patients in the different quartile groups were included in each graph. (B) Receiver operating characteristic curves for the patients with STEMI vs. control subjects for Kyn. (C) Restricted cubic spline modeling indicated the relationship between the plasma Kyn levels and the risk of MACCE. The solid line indicated the hazard ratios and the shaded areas, the 95% confidence intervals. (D) Forest plots showed that Kyn levels were associated with the prognosis in STEMI patients of subgroups according the STEMI prognostic analysis cohort data, after adjusting for per-standard deviation odds ratio (95% confidence interval) for the plasma.