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. Author manuscript; available in PMC: 2022 Nov 16.
Published in final edited form as: Am J Obstet Gynecol MFM. 2021 Jun 19;3(5):100420. doi: 10.1016/j.ajogmf.2021.100420

TABLE 2.

Adjusted odds ratiosa of severe maternal morbidity with and without transfusion by prepregnancy body mass index

SMM Underweight (BMI <18.5), aOR (95% CI) Class I obesity (BMI 30–34.9), aOR (95% CI) Class II obesity (BMI 35–39.9), aOR (95% CI) Class III obesity (BMI 40–49.9), aOR (95% CI) Super obesity (BMI ≥50), aOR (95% CI)
Acute renal failure 1.24 (0.75–2.04) 1.26 (0.92–1.72) 1.32 (0.84–2.08) 2.01 (1.22–3.32)b 4.42 (1.80–10.81)b
Adult respiratory distress syndrome 0.72 (0.39–1.32) 0.94 (0.67–1.31) 1.41 (0.93–2.14) 2.08 (1.31 –3.30)b 1.56 (0.39–6.29)
Disseminated intravascular coagulation 0.77 (0.55–1.09) 0.79 (0.63–1.00) 1.06 (0.78–1.45) 0.75 (0.45–1.23) 1.16 (0.37–3.62)
Eclampsia 0.86 (0.45–1.63) 1.05 (0.71 –1.56) 0.79 (0.40–1.55) 2.46 (1.44–4.21)b 1.28 (0.18–9.19)
Heart failure during procedure or surgery 0.58 (0.14–2.41) 1.52 (0.82–2.82) 2.37 (1.11 –5.07)b 4.95 (2.38–10.29)b 13.68 (4.17–44.87)b
Puerperal cerebrovascular disorders 0.87 (0.35–2.14) 0.65 (0.36–1.20) 0.41 (0.13–1.29) 2.02 (0.97–4.20) 3.96 (0.96–16.25)
Pulmonary edema or acute heart failure 0.27 (0.08–0.83) 1.07 (0.74–1.53) 1.51 (0.95–2.39) 2.38 (1.45–3.90)b 1.94 (0.48–7.88)
Severe anesthesia complications 1.41 (0.61–3.27) 1.95 (1.17–3.25)b 2.52 (1.28–4.96)b 3.85 (1.82–8.15)b 4.13 (0.57–30.09)b
Sepsis 0.94 (0.51 –1.74) 1.63 (1.17–2.27)b 1.48 (0.89–2.45) 2.25 (1.29–3.91)b 1.21 (0.17–8.69)
Air and thrombotic embolism 1.22 (0.57–2.65) 1.14 (0.71–1.82) 1.42 (0.76–2.67) 1.69 (0.78–3.67) 5.61 (1.76–17.90)b
Blood transfusion 0.93 (0.82–1.05) 1.03 (0.95–1.11) 1.11 (0.99–1.24) 1.23 (1.07–1.43)b 1.74 (1.24–2.45)b
Hysterectomy 0.74 (0.46–1.21) 0.96 (0.74–1.26) 1.24 (0.86–1.78) 1.29 (0.79–2.12) 1.85 (0.59–5.81)
Ventilation 0.77 (0.28–2.11) 1.1 (0.64–1.86) 1.58 (0.81 –3.08) 4.25 (2.41 –7.49)b 15.15 (6.86–33.45)b
Mortality 1.22 (0.28–5.22) 0.18 (0.02–1.31) 0.44 (0.06–3.24) 1.66 (0.39–7.12) 5.92 (0.79–44.67)
Total SMM events 0.99 (0.90–1.08) 1.06 (1.00–1.12) 1.14 (1.05–1.24)b 1.34 (1.21 –1.49)b 1.99 (1.57–2.54)b

The following SMM cases were not included in the table because there were too few cases for estimation: acute myocardial infarction, amniotic fluid embolism, aneurysm, cardiac arrest/ventricular fibrillation, conversion of cardiac rhythm, shock, sickle cell disease with crisis, temporary tracheostomy.

aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; DIC, XXX; SMM, severe maternal morbidity.

a

Adjusted for maternal age, race and ethnicity, education level, insurance, neighborhood poverty level, parity, smoking, and prenatal care adequacy.

b

Indicates statistically significant results.