Table 2.
Laboratory results during the first 24 hours after PICU admission
| Total patients (n=60) |
Acute respiratory failure | P value‡ | ||
| Absent (n=34) | Present (n=26) | |||
| Haemoglobin, g/dL | 13.0 (10.4–15.0) | 12.7 (10.0–15.1) | 13.4 (10.7–14.9) | 0.665 |
| Haematocrit, % | 38.3 (31.7–44.7) | 37.6 (30.7–44.9) | 39.8 (33.7–44.1) | 0.743 |
| White blood cell count, 103/mm3 | 6.2 (3.1–9.2) | 4.6 (2.9–8.0) | 8.0 (4.4–16.0) | 0.022 |
| Neutrophil, % | 50.3 (31.3–63.3) | 44.5 (18.8–59.5) | 56.4 (46.0–64.2) | 0.023 |
| Lymphocyte, % | 27.0 (14.3–42.1) | 31.9 (16.8–51.5) | 18.5 (14.0–35.7) | 0.205 |
| Band form, % | 2.3 (0.0–11.3) | 2.7 (0.0–10.7) | 1.0 (0.0–13.3) | 0.880 |
| Atypical lymphocyte, % | 4.5 (1.3–8.8) | 4.9 (1.3–12.6) | 4.2 (1.3–6.8) | 0.361 |
| Platelet, 103/mm3 | 22.0 (15.0–46.0) | 21.5 (13.0–46.0) | 23.5 (15.0–49.3) | 0.571 |
| Prothrombin time, s | 14.6 (12.7–16.5) | 14.0 (12.5–15.2) | 16.2 (13.8–25.6) | 0.007 |
| INR, s | 1.3 (1.1–1.5) | 1.3 (1.1–1.3) | 1.4 (1.2–2.3) | 0.345 |
| Partial thromboplastin time, s | 42.5 (35.6–54.5) | 38.5 (32.1–43.3) | 57.0 (42.7–60.5) | < 0.001 |
| Fibrinogen, mg/dL | 117.4 (87.2–171.4) | 130.0 (82.1–172.7) | 113.8 (87.4–170.2) | 0.687 |
| Albumin, mg/dL | 2.8 (2.3–3.4) | 2.8 (2.2–3.5) | 2.8 (2.3–3.4) | 0.811 |
| AST, U/L | 215.5 (105.3–1253.3) | 185.5 (90.5–433.3) | 446.5 (113.5–3292.0) | 0.080 |
| ALT, U/L | 73.0 (37.0–296.5) | 63.5 (28.8–146.5) | 120.0 (37.0–894.8) | 0.187 |
| ALP, U/L | 102.0 (69.0–125.0) | 100.0 (68.0–121.0) | 115.5 (73.5–142.5) | 0.303 |
| Total bilirubin, mg/dL | 0.40 (0.21–1.33) | 0.31 (0.20–0.78) | 0.63 (0.22–2.58) | 0.136 |
| Direct bilirubin, mg/dL | 0.20 (0.10–0.59) | 0.17 (0.10–0.41) | 0.23 (0.10–1.86) | 0.135 |
| BUN, mg/dL | 10.8 (7.5–19.3) | 9.9 (7.2–15.8) | 11.4 (7.5–24.9) | 0.447 |
| Creatinine, mg/dL | 0.52 (0.36–0.85) | 0.49 (0.38–0.82) | 0.57 (0.36–1.02) | 0.660 |
| Estimated GFR, mL/min/1.73 m2* | 86.4 (69.5–124.2) | 95.0 (71.0–125.2) | 82.9 (57.2–117.8) | 0.257 |
| Bicarbonate, mmol/L | 17.0 (14.0–19.0) | 17.5 (14.0–20.0) | 16.0 (13.0–18.0) | 0.096 |
| Lactate, mmol/L (N1=13/34, N2=12/26)† | 3.3 (2.2–5.8) | 2.5 (1.6–3.9) | 4.7 (2.4–8.7) | 0.087 |
| Arterial pH (N1=17/34, N2=22/26)† | 7.40 (7.34–7.42) | 7.42 (7.38–7.46) | 7.36 (7.25–7.41) | 0.006 |
*Estimated GFR is calculated using modified Schwartz formular.
†N1=number of patients who did not require respiratory support. N2=number of patients who were supported with NIV/MV.
‡Pearson’s χ2 test or Fisher’s exact test for qualitative data whereas Mann-Whitney U test for quantitative data.
§
ALP, Alkaline phosphatase; BUN, blood urea nitrogen; GFR, glomerulous filtration rate; MV, mechanical ventilation; NIV, non-invasive ventilation; PICU, paediatric intensive care unit.