Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Possible combinations of cell-surface molecules defining TRM cells
| Function | Surface marker | Combinations of markers defining TRM cells | ||||||
|---|---|---|---|---|---|---|---|---|
| Tissue-retention | CD103 | + | + | + | – | + | – | – |
| CD49a | + | + | – | + | – | + | – | |
| CXCR6 | + | – | + | + | – | – | + | |
| Recirculation | S1PR1 | – | – | – | – | – | – | – |
| S1PR5 | – | – | – | – | – | – | – | |
The expression of at least one of the molecules mediating tissue retention and the simultaneous lack of receptors guiding T cell egress from tissues is required to define TRM cells. “ + ”, expression; “–”, lack of expression.
