Table 1. Clinical and laboratory findings in the studies patients ( n = 201) .
| All patients N = 201 |
Normal osmesis N = 77 |
Hyposmia N = 49 |
Anosmia N = 75 |
P -value | |
|---|---|---|---|---|---|
| Age (years) median (IQR) | 31.0 (27.0- 36.0) | 33.0 (28.0–39.0) | 32.0 (28.5–38.0) | 30.0 (26.0–33.0) | 0.003 |
| Male/female n | 132/69 | 47/30 | 35/14 | 50/25 | 0.48 |
| Covid-19 severity n (%) | |||||
| Mild | 30 (14.9) | 65 (84.4) | 38 (77.6) | 68 (90.7) | 0.13 |
| Severe | 171 (85.1) | 12 (15.6) | 11 (22.4) | 7 (9.3) | |
| Laboratory findings median (IQR) | |||||
| Hb (gm/dL) | 13.0 (12.0–14.0) | 12.8 (11.8–14.0) | 13.0 (11.5–14.2) | 13.2 (12.0–14.0) | 0.27 |
| WBCs (× 103/mL) | 6.5 (4.5- 10.0) | 6.5 (4.0–10.0) | 6.0 (4.6–10.7) | 7.0 (4.5–10.0) | 0.44 |
| Platelets (× 103/mL) | 212.0 (162.5- 260.0) | 200.0 (139.5–250.0) | 200.0 (160.0–239.5) | 215.0 (180.0–259.0) | 0.17 |
| CRP (mg/dL) | 88.0 (44.5- 126.5) | 91.0 (41.0–145.5) | 93.0 (50.5–122.5) | 75.0 (41.0–118.0) | 0.42 |
| Procalcitonin (µg/L) | 0.1 (0.08- 0.2) | 0.1 (0.1–0.2) | 0.15 (0.08–0.2) | 0.1 (0.08–0.2) | 0.96 |
| LDH (U/L) | 614.0 (414.0- 908.0) | 527.0 (385.5–922.5) | 621.0 (454.5–911.5) | 618.0 (431.0–831.0) | 0.38 |
| Ferritin (µg/L) | 663.0 (442.0- 1,456.5) | 648.0 (408.5–1,549.0) | 800.0 (416.0–1,598.5) | 713.0 (507.0–1,324.0) | 0.65 |
| PT (sec.) | 13.9 (13.0–15.8) | 14.3 (13.2–15.8) | 14.8 (13.3–16.7) | 14.5 (13.0–16.0) | 0.36 |
| APTT (sec.) | 34.0 (30.0–42.0) | 35.0 (31.0–40.5) | 36.0 (32.0–45.5) | 33.0 (30.0–44.0) | 0.27 |
| D-dimer (ng/mL) | 1162.0 (746.5- 2,122.0) | 978.0 (732.0–2,122.0) | 1290.0 (810.0–2,549.0) | 980.0 (750.0–1,750.0) | 0.35 |
| Fibrinogen (gm/dL) | 3.7 (3.0- 4.8) | 3.7 (3.1–4.7) | 4.1 (3.0–5.2) | 3.5 (3.0–4.5) | 0.23 |
| Creatinine (mg/dL) | 1.1 (0.8- 1.3) | 1.0 (0.9–1.3) | 0.9 (0.9–1.25) | 0.9 (0.8–1.3) | 0.1 |
| Urea (mg/dL) | 50.0 (38.0–76.0) | 51.0 (38.0–76.5) | 56.0 (41.0–80.0) | 45.0 (37.0–72.0) | 0.42 |
| Albumin (gm/dL) | 3.2 (3.0- 4.0) | 3.5 (3.0–3.9) | 3.5 (3.1–3.8) | 3.5 (3.1–4.0) | 0.88 |
| AST (U/L) | 45.0 (29.0–72.5) | 47.0 (34.5–76.0) | 41.0 (28.0–76.0) | 42.0 (27.0–67.0) | 0.19 |
| ALT (U/L) | 51.0 (34.0- 80.0) | 59.0 (37.0–81.0) | 48.0 (33.0–80.0) | 44.0 (26.0–76.0) | 0.08 |
| O2 saturation (%) | 90.0 (80.0- 95.0) | 92.0 (80.0–95.0) | 90.0 (80.0–94.0) | 92.0 (85.0–95.0) | 0.07 |
| Vitamin B12 (pg/mL) | 403.0 (212.0- 544.5) | 491.0 (364.5–584.5) | 363.0 (198.0–539.0) | 337.0 (175.0–467.0) | < 0.001 |
Abbreviations: aPTT, activated partial thromboplastin time; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, c-reactive protein; Hb, hemoglobin; IQR, interquartile range; LDH, lactate dehydrogenase; PT, prothrombin time; WBCs, white blood cells.