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. 2022 Feb 23;16(6):952–963. doi: 10.5009/gnl210391

Table 4.

Meta-Regression for Diagnostic Odds Ratio of Each Measurement

Variable FIB-4 for AF NFS for AF
Coefficient (95% CI) p-value Coefficient (95% CI) p-value
Mean age, yr 0.063 (0.022 to 0.104) 0.002 0.095 (0.048 to 0.143) <0.001
Proportion of male, % –0.019 (–0.037 to –0.001) 0.034 –0.022 (–0.043 to –0.001) 0.040
DM, % 0.005 (–0.011 to 0.021) 0.561 0.013 (–0.001 to 0.028) 0.065
HTN, % 0.028 (–0.001 to 0.045) 0.055 0.021 (–0.003 to 0.046) 0.089
Dyslipidemia, % –0.009 (–0.067 to 0.048) 0.747 0.005 (–0.028 to 0.039) 0.758
Mean BMI, kg/m2 0.004 (–0.086 to 0.095) 0.919 0.062 (–0.032 to 0.156) 0.196
Mean waist, cm –0.009 (–0.075 to 0.056) 0.774 0.001 (–0.070 to 0.071) 0.997
Mean AST –0.020 (–0.041 to 0.001) 0.060 –0.023 (–0.047 to 0.001) 0.055
Mean ALT –0.014 (–0.026 to –0.002) 0.017 –0.018 (–0.032 to –0.005) 0.007

FIB-4, fibrosis-4; AF, advanced fibrosis; NFS, nonalcoholic fatty liver disease (NAFLD) fibrosis score; CI, confidence interval; DM, diabetes mellitus; HTN, hypertension; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase.