NCT02004171.

Study name	Electronic cigarettes or nicotine inhaler for smoking cessation
Methods	Randomized controlled trial, open‐label safety/efficacy study Setting and recruitment not specified, USA
Participants	40 participants Inclusion criteria: 18‐60 years old Meet DSM‐IV criteria for nicotine dependence Seeking treatment for smoking cessation Smoking at least 15 cpd Exclusion criteria: DSM‐IV diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder Current diagnosis of major depressive disorder Current diagnosis for other psychiatric disorders that may require intervention over course of study Receiving treatment for nicotine dependence Pregnancy, lactation, or chance of pregnancy Unstable medical condition Substance abuse diagnosis Use of cannabis or alcohol on more than 20 days in past 30 days Suicide risk
Interventions	4 weeks: ECs (2nd generation) with 24 mg nicotine cartridges, 1‐2 cartridges daily Nicotine inhaler with 10 mg cartridges, max 16 cartridges per day
Outcomes	Over 4 weeks: cpd Withdrawal Benefits from smoking cessation (breathing, sense of taste and smell, physical fitness) Adverse events BMI
Starting date	December 2013
Contact information	Barney Vaughan, vaughan@nyspi.columbia.edu
Notes