Figure 2.

Illustration of the interactive visualization tool for a select set of ventilation criteria: minimum Fio₂ (ΔminFio₂) greater than or equal to 20%, minimum positive end-expiratory pressure (ΔminPEEP) greater than or equal to 3 (n = 14,517; ventilator-associated condition [VAC] = 1,366; no VAC = 13,151). On each heatmap, the cell surrounded by a blue box corresponds to the criteria selected in this example (ΔminFio₂ ≥ 20%, ΔminPEEP ≥ 3). The upper left graph represents the Kaplan-Meier survival curves among patients with VAC versus patients without VAC (“no VAC”) resulting from the selected set of clinical criteria, whereas the upper right panel illustrates variability in mortality odds ratios across changes in ΔminFio₂ and ΔminPEEP. In addition, the lower panels showcase differences in ICU (left) and hospital (right) length of stay outcomes. Although the estimated probabilities of survival clearly distinguish VAC patients from others until the 15th day following the start of mechanical ventilation, they fully overlap from the 16th day onward (p = 0.063).