Table 1.
Demographics and clinical variables for remission and response in the NeuroPharm dataset. HAMD-6: Hamilton Depression Rating Scale-6 item.
Response | Remission | |||||
---|---|---|---|---|---|---|
Characteristic | Non-responder, N = 331 | Responder, N = 461 | p-value2 | Non-remitter, N = 451 |
Remitter, N = 341 |
p-value2 |
Age | 24 (22, 27) | 25 (23, 29) | 0.2 | 24 (22, 27) | 26 (23, 29) | 0.14 |
Sex | 0.4 | 0.13 | ||||
Female | 26 (79 %) | 32 (70 %) | 36 (80 %) | 22 (65 %) | ||
Male | 7 (21 %) | 14 (30 %) | 9 (20 %) | 12 (35 %) | ||
HAMD-6 - Baseline | 12 (11, 13) | 12 (12, 13) | 0.9 | 13 (12, 13) | 12 (11.25, 13) | 0.2 |
HAMD-6 - Week 8 | 9 (7, 11) | 3 (2, 5) | <0.001 | 8 (6, 10) | 2 (1, 3) | <0.001 |
Recurrence status | 0.5 | 0.6 | ||||
First-episode | 12 (36 %) | 20 (43 %) | 17 (38 %) | 15 (44 %) | ||
Recurrent | 21 (64 %) | 26 (57 %) | 28 (62 %) | 19 (56 %) |
Median (IQR); n (%)
Wilcoxon rank sum exact test; Pearson's Chi-squared test; Wilcoxon rank sum test