Table 1.
Hippocampal mRNA levels of IL-10 11 months post-GWI exposure and delayed LNFPIII treatment. The effect of GWI exposure and delayed LNFPIII treatment on the expression of anti-inflammatory cytokine IL-10 in the dorsal and ventral hippocampus measured by qPCR. Hippocampal samples from mice (n = 4–6/treatment) were used for RNA isolation and subsequent qPCR analyses. Data were analyzed by the 2−ΔΔCt method with 18S as the housekeeping gene and are expressed as a mean fold change from the Vehicle-Vehicle group ±SE. * indicates significant fold change from Vehicle-Vehicle, p < 0.05, and values are bolded. ˆ indicates p < 0.10.
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Table 1. Hippocampal IL-10 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Vehicle-LNFPIII |
GWI-Vehicle |
GWI-LNFPIII |
GWI-Vehicle vs GWI-LNFPIII |
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| Region | fold change | se | p value | fold change | se | p value | fold change | se | p value | p value |
| Dorsal | 0.95 | 0.43 | 0.89 | 1.15 | 0.73 | 0.74 | 1.04 | 0.26 | 0.90 | 0.83 |
| Ventral | 1.41 | 0.38 | 0.48 | 1.11 | 0.34 | 0.84 | 3.41 | 4.15 | 0.03* | 0.08 ˆ |