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. 2022 Nov 8;26:100553. doi: 10.1016/j.bbih.2022.100553

Table 1.

Hippocampal mRNA levels of IL-10 11 months post-GWI exposure and delayed LNFPIII treatment. The effect of GWI exposure and delayed LNFPIII treatment on the expression of anti-inflammatory cytokine IL-10 in the dorsal and ventral hippocampus measured by qPCR. Hippocampal samples from mice (n = 4–6/treatment) were used for RNA isolation and subsequent qPCR analyses. Data were analyzed by the 2−ΔΔCt method with 18S as the housekeeping gene and are expressed as a mean fold change from the Vehicle-Vehicle group ±SE. * indicates significant fold change from Vehicle-Vehicle, p < 0.05, and values are bolded. ˆ indicates p < 0.10.

Table 1. Hippocampal IL-10

Vehicle-LNFPIII
GWI-Vehicle
GWI-LNFPIII
GWI-Vehicle vs GWI-LNFPIII
Region fold change se p value fold change se p value fold change se p value p value
Dorsal 0.95 0.43 0.89 1.15 0.73 0.74 1.04 0.26 0.90 0.83
Ventral 1.41 0.38 0.48 1.11 0.34 0.84 3.41 4.15 0.03* 0.08 ˆ