Table 2.
Study | Number of patients | Number of healthy controls | Method | Main Finding Hippocampus | Agreement with our Findings |
---|---|---|---|---|---|
Brandt et al., 2005 | 10 | 10 | Manual | Volume loss | No |
Göttlich et al., 2016 | 27 | 29 | VBM SPM12 | No change | Yes |
Kremmyda et al., 2016 | 15 | 15 | VBM SPM8 | Volume loss mid-hippocampus | – |
Cutfield et al., 2014 | 12 | 15 | VBM FSL | No change | Yes |
van Cruijsen et al., 2007 | 10 | 10 | Manual | No change | Yes |
zu Eulenburg et al., 2010 | 22 | 22 | VBM SPM5 | Decreased intensities left posterior hippocampus | – |
Seo et al., 2016 | 38 | 76 | Manual | Volume loss | No |
Hüfner et al., 2007 | 16 | 16 | Manual / VBM SPM21 | No change | Yes |
Hüfner et al., 2009 | 16 | 16 | VBM SPM2 | No change | Yes |
Helmchen et al., 2009 | 15 | 15 | VBM SPM2 | No change | Yes |
Helmchen et al., 2010 | 15 | 15 | VBM SPM2 | No change | Yes |
Hong et al., 2014 | 9 | – | VBM SPM8 | −2 | – |
This Study | 55 | 39 | FreeSurfer 6 |
1 Manual tracing of hippocampus / SPM2 for cortex.
2 Longitudinal study, no comparison to healthy control group.