Table 1.
Demographic and clinical characteristics of subjects.
| Variables | R-MDD | NR-MDD | HC | T/F/Z/χ2 | P |
|---|---|---|---|---|---|
| Numbers of subjects | 31 | 35 | 57 | – | – |
| Age | 29.77 ± 10.54 | 25.83 ± 8.14 | 30.51 ± 7.76 | 3.355 | 0.038a |
| Gender (male/female) | 13/18 | 12/23 | 26/31 | 1.150 | 0.563b |
| Education (years) | 12.13 ± 3.16 | 13.29 ± 3.04 | – | −1.513 | 0.135c |
| Course of disease (months) | 29.15 ± 28.01 | 26.67 ± 27.45 | – | 0.362 | 0.719c |
| First-episode of depression (yes/no) | 16/15 | 19/16 | – | 0.047 | 0.828b |
| Age at onset(years) | 27.45 ± 10.53 | 23.71 ± 8.22 | −1.630 | 0.103d | |
| Heavy alcohol users(yes/no) | 2/29 | 3/32 | – | 0.558e | |
| Baseline HAMD-17 | 22.39 ± 4.37 | 23.74 ± 4.92 | – | −1.128 | 0.259d |
| Baseline HAMA-14 | 17.00 ± 6.23 | 23.11 ± 5.97 | −4.069 | 0.001c | |
| Antidepressant regimen(Escitalopram/Venlafaxine) | 16/15 | 14/21 | 0.894 | 0.344b | |
| Fluoxetine equivalent dosage regimen(mg) | 27.74 ± 12.96 | 31.29 ± 13.68 | −1.039 | 0.299d |
Abbreviations: R, remitters; NR, Non-remitters; MDD, major depressive disorder; HC, healthy controls; HAMD-17, 17-item Hamilton Depression Rating Scale; HAMA-14, Hamilton Anxiety Scale.
a
One-way ANOVA.
b
Chi-square test.
c
Two-sample t-test.
d
Mann-Whitney U.
e
Fisher’s exact test.