Fig. 5.
Group differences and correlations with frontoparietal across-state overall connectivity. Panel a: (Left) Patients with mild to moderate disability have higher across-state overall connectivity (ASOC) between the frontoparietal network (FPN) and the rest of the brain compared to patients with no disability; (Middle) Patients with mild to moderate disability have lower ASOC between the FPN and basal ganglia (BG) compared to patients with no disability, with a similar trend compared to HCs; (Right) Patients with mild to moderate disability have higher ASOC between the SMN) compared to both patients with no demonstrated disability and HC. Panel b: FPN overall connectivity with the BG is negatively correlated with fatigue (left) and motor impairment (right); Asterisks denote significance level: * = pFDR < 0.05.