Table 2.
Methods of assessing auto-contouring using deep learning contouring (DLC) for head and neck organs at risk.
| Centre 1 | Centre 2 | Centre 3 | Centre 4 | |
|---|---|---|---|---|
| Number of patients for timing | 10 Manual, 10 DLC | 20 manual, 20 DLC | 9 manual, 7 DLC | 40 manual, 169 DLC |
| Number of patients for quantitative analysis | 10 | 10 | 10 | 15 |
| Same patients for timing and quantitative analysis? | Y | N | N | N |
| Timing Study design | Paired | Unpaired | Unpaired | Unpaired |
| Number of staff | 4 (all 4 outlined all 10 patients) | 3 | 1 | 6 |
| Staff group | Clinicians | Radiotherapy Planners | Clinicians | Radiotherapy Planners |
| CT scanner and slice thickness | Philips Brilliance Big Bore (3 mm) | GE Discovery (2.5 mm) | GE Discovery (2.5 mm) | Philips Brilliance Wide Bore, Siemens Confidence (3 mm) |
| Existing method | Manual | Atlas | Manual | Manual |
| DLCExpert model name | Combined: 2 local and 1 generic H&N_CT_NL004_GN | H&N_CT_NL004_GN | H&N CT NL004 GN | H&N_CT_NL004_GN |
| DLCExpert model description | Generic model based on data from a centre in the Netherlands used for mandible and SMGs. Models based on local data used for other contours. | Generic model based on data from a centre in the Netherlands. | Generic model based on data from a centre in the Netherlands. | Generic model based on data from a centre in the Netherlands. |
| Number of images for training model | 698 (generic),72 (local model A), 69 (local model B) | 698 | 698 | 698 |
| DLC OARs | Eyes, parotids, submandibular glands, brainstem, larynx, mandible, oral cavity, spinal cord | Brainstem mandible, parotids, spinal cord | Brainstem, parotids, spinal cord | Mandible, parotids, submandibular glands |
| OARs from other source | Atlas for orbits, optic nerves, lens | Atlas for orbits, optic nerves, lens | ||
| Editing software | Pinnacle v16 (Philips, NL) | RayStation v7 (RaySearch, Sweden) | Eclipse v13.7 (Varian Medical Systems, Palo Alto, USA) | Eclipse v15.6 MR5 (Varian Medical Systems, Palo Alto, USA) |
| Outlining protocol basis | DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines | DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines | DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines | DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines |
| Timing method | Manual - time to draw or edit OARs timed by the staff member | Manual- time to draw or edit OARs timed by the staff member | Manual-time to draw or edit OARs timed by the staff member | Aria (with greater than 3 h and < 10 min removed) |