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. 2022 Apr 30;32(11):7800–7810. doi: 10.1007/s00330-022-08733-3

Table 5.

Preoperative characteristics of patients with and without improved secondary outcomes a year after surgery

Characteristic iNPHGS total iNPHGS gait iNPHGS cognitive iNPHGS urinary
Improvement (n = 29) No improvement (n = 18) p value Improvement (n = 24) No improvement (n = 23) p value Improvement (n = 20) No improvement (n = 27) p value Improvement (n = 14) No improvement (n = 33) p value
Demographic information
  Age (years) 67.0 ± 8.8 66.8 ± 9.9 0.958 66.5 ± 9.5 67.2 ± 9.0 0.854 66.7 ± 8.9 67.1 ± 9.4 0.919 65.1 ± 8.1 67.6 ± 9.5 0.552
  Duration of symptoms 12 (6–24) 12 (5–62) 0.807 12 (6–33) 12 (5–48) 0.765 12 (6–20) 15 (7–60) 0.301 6 (3–24) 12 (11–51) 0.357
Preoperative clinical outcomes
  mRS score 2.0 (2.0–4.0) 2.0 (1.8–3.0) < 1.0 2.0 (1.0–3.3) 2.0 (2.0–3.0) 0.428 2.0 (2.0–4.0) 2.0 (1.3–3.0) 0.598 2.0 (1.0–4.0) 2.0 (2.0–3.0) 0.976
  iNPHGS score 6.0 (5.0–8.0) 5.5 (3.0–7.0) 0.311 6.5 (4.8–7.3) 6.0 (3.0–7.0) 0.605 6.0 (5.0–8.5) 6.0 (3.3–7.0) 0.419 7.0 (6.0–8.0) 5.0 (3.0–7.0) 0.11
MRI findings
  DESH score 6.0 (5.0–6.0) 4.0 (3.0–6.3) 0.238 6.0 (4.0–6.3) 5.0 (4.0–6.0) 0.461 6.0 (4.5–6.0) 5.0 (3.3–6.0) 0.388 6.0 (5.0–6.0) 5.5 (4.0–6.0) 0.657
  iNPH Radscale 8.0 (8.0–10.0) 7.5 (5.8–10.0) 0.397 8.0 (7.5–10) 8.0 (6.0–10.0) 0.643 8.0 (7.0–9.0) 8.0 (6.3–10.0) 0.803 9.0 (8.0–10.0) 8.0 (6.0–10.0) 0.244
  EI 0.37 (0.33–0.41) 0.36 (0.32–0.41) 0.756 0.36 (0.34–0.41) 0.36 (0.32–0.41) 0.978 0.37 (0.34–0.43) 0.36 (0.32–0.41) 0.677 0.34 (0.32–0.45) 0.37 (0.33–0.40) 0.657
  CA 83.0 (75.0–93.0) 91.0 (78.5–104.0) 0.177 83.5 (73.3–93.3) 86.0 (79.0–97.0) 0.285 84.0 (79.0–89.5) 85.5 (72.0–96.8) 0.677 84.0 (75.0–96.0) 85.0 (74.3–95.3) 0.79

Nonparametric data are presented as median (interquartile range). Significant difference was determined using the Mann-Whitney U test

iNPHGS idiopathic normal pressure hydrocephalus grading scale, MRI magnetic resonance imaging, mRS modified Rankin Scale, DESH disproportionately enlarged subarachnoid space hydrocephalus, EI Evans’ index, CA callosal angle