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. 2022 Nov 16;12:19705. doi: 10.1038/s41598-022-22457-w

Table 4.

GO analysis molecular function by Enrichr.

Gene ontology p-value Adjusted p-value Odds Ratio Combined score
Immunoglobulin receptor binding (GO:0034987)  < 0.001 0.004 216.83 2034.63
Carbonate dehydratase activity (GO:0004089)  < 0.001 0.008 96.34 779.62
Platelet-derived growth factor receptor binding (GO:0005161)  < 0.001 0.009 78.82 610.51

Proteins that correlated with PC1 or PC2 and were increased among patients with AKI as compared to patients without AKI were used to identify pathways affected by sepsis-AKI.