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. 2022 Nov 3;9:992252. doi: 10.3389/fcvm.2022.992252

TABLE 3.

Univariate and multivariate cox regression analysis results for MACE.

Variables Univariate analysis
Multivariate analysis
Crude HR
Crude
Model 1
Model 2
(95% CI) P-value Adjusted HR
Adjusted
Adjusted HR
Adjusted
(95% CI) P-value (95% CI) P-value
Duration of diabets 1.030 (1.012–1.049) 0.001 1.019 (1.000–1.039) 0.051 1.022 (1.003–1.042) 0.025
D-Dimer (mg/L) 1.037 (1.005–1.070) 0.022 0.981 (0.945–1.019) 0.321 1.018 (0.981–1.055) 0.349
Neut, 109/L 1.105 (1.062–1.149) <0.001 1.027 (0.983–1.078) 0.219 1.068 (1.021–1.117) 0.004
NT-pro BNP (pmol/L) 1.000 (1.000–1.000) <0.001 1.000 (1.000–1.000) 0.015 1.000 (1.000–1.000) 0.002
Fibrinogen (g/L) 1.307 (1.150–1.486) <0.001 1.125 (0.992–1.276) 0.066 1.129 (0.992–1.285) 0.067
LVEF (%) 1.006 (1.003–1.009) <0.001 0.976 (0.959–0.993) 0.005 0.973 (0.956–0.989) 0.001
FPG (mmol/L) 1.121 (1.094–1.149) <0.001 0.933 (0.888–0.981) 0.007
HbA1c (%) 1.251 (1.206–1.298) <0.001 1.406 (1.313–1.510) <0.001
HGI 1.531 (1.422–1.648) <0.001 1.473 (1.365–1.589) <0.001
GRACE risk score 1.010 (1.005–1.014) <0.001 0.999 (0.994–1.004) 0.69 1.000 (0.996–1.005) 0.896

Neut, neutrophils; HbA1c, glycosylated hemoglobin; FPG, fasting blood glucose; LVEF, left ventricular ejection fractions; HGI, hemoglobin glycation index.