TABLE 3.

Comparison of diagnostic performance for advanced hepatic fibrosis (MRE cut-off values ≥ 3.6) according to the various cut-off values of FIB-4.

	Sensitivity	Specificity	PPV	NPV	Accuracy
FIB-4 to use low cut-off; 1.3 (2.0)
Total subjects	69.6	77.5	4.9	99.3	77.4
Metabolically healthy group	64.0	78.2	2.2	99.6	78.1
FIB-4 to use low cut-off; 0.9
Total subjects	92.2	42.1	2.6	99.7	42.9
Metabolically healthy group	100.0	43.6	1.3	100	44.0
FIB-4 to use low cut-off; 1.0
Total subjects	90.2	52.2	3.1	99.7	52.8
Metabolically healthy group	96.0	53.8	1.6	99.9	54.1
FIB-4 to use low cut-off; 1.1
Total subjects	87.3	60.9	3.6	99.7	61.3
Metabolically healthy group	92.0	61.9	1.8	99.9	62.2
FIB-4 to use low cut-off; 1.2
Total subjects	83.3	69.0	4.3	99.6	69.2
Metabolically healthy group	80.0	69.8	2.0	99.8	69.9
FIB-4 to use low cut-off; 1.3
Total subjects	75.5	75.4	4.9	99.5	75.4
Metabolically healthy group	76.0	76.7	2.4	99.8	76.7

FIB-4, fibrosis-4 index; MRE, magnetic resonance elastography; NFS, non-alcoholic fatty liver disease fibrosis score; NPV, negative predictive value; PPV, positive predictive value.