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. 2022 Nov 3;9:1024836. doi: 10.3389/fmed.2022.1024836

TABLE 4.

Comparison of AUROC for hepatic fibrosis between FIB-4 and NFS in various groups according to different MRE cut-off values.

MRE cut-off AUROC
P-value
FIB-4 NFS
Total 3.2 0.709 0.699 0.803
3.4 0.751 0.745 0.761
3.6 0.840 0.798 0.036
3.8 0.867 0.843 0.174
4.0 0.896 0.877 0.529
Non-fatty liver group 3.2 0.728 0.682 0.151
3.4 0.759 0.706 0.129
3.6 0.872 0.777 0.01
3.8 0.925 0.867 0.122
4.0 0.933 0.900 0.467
Metabolically healthy group 3.2 0.732 0.631 <0.001
3.4 0.756 0.638 0.001
3.6 0.862 0.702 0.001
3.8 0.913 0.808 0.03
4.0 0.956 0.880 0.105
Fatty liver group 3.2 0.704 0.704 0.706
3.4 0.752 0.76 0.671
3.6 0.823 0.806 0.389
3.8 0.841 0.824 0.336
4.0 0.876 0.860 0.622
Metabolically unhealthy group 3.2 0.695 0.688 0.984
3.4 0.744 0.742 0.899
3.6 0.828 0.800 0.08
3.8 0.85 0.823 0.111
4.0 0.878 0.852 0.346

Metabolically healthy group was defined as sharing less than two metabolic risks and not having diabetes. AUROC, area under the receiver operating characteristic curve; FIB-4, fibrosis-4 index; MRE, magnetic resonance elastography; NFS, non-alcoholic fatty liver disease fibrosis score.