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. 2022 Nov 3;9:990755. doi: 10.3389/fnut.2022.990755

TABLE 2.

Associations between dietary n 3 PUFAs and breast cancer riska.

Cases/Controls Crude-OR (95% CI) P-trend Adjusted-OR (95% CI) P-trend
Dietary ALA 0.005 0.005
 T1 328/287 1.00 (Ref.) 1.00 (Ref.)
 T2 287/287 0.88 (0.70–1.10) 0.89 (0.70–1.12)
 T3 235/287 0.72 (0.57–0.91) 0.70 (0.55–0.90)
Dietary long-chain n 3 PUFAs 0.010 0.025
 T1 340/287 1.00 (Ref.) 1.00 (Ref.)
 T2 255/287 0.75 (0.59–0.94) 0.77 (0.60–0.97)
 T3 255/287 0.74 (0.59–0.94) 0.76 (0.60–0.97)
Dietary total n 3 PUFAs 0.014 0.015
 T1 319/287 1.00 (Ref.) 1.00 (Ref.)
 T2 294/287 0.92 (0.73–1.16) 0.95 (0.75–1.20)
 T3 237/287 0.74 (0.59–0.94) 0.74 (0.58–0.94)

ALA, α-linolenic acid; CI, confidence interval; OR, odds ratio; PUFA, polyunsaturated fatty acid; T, tertile.

aAdjusted for age, BMI, MET-h/week, education, passive smoking, regular drinking, first-degree relatives with cancer and energy intake.