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. 2022 Nov 3;13:1057746. doi: 10.3389/fimmu.2022.1057746

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Copyright © 2022 Peng and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NLRP3 depletion in macrophages alters genes associated with macrophage phenotype. (A-C) A GEO database GSE183698 was used to analyzed gene profile from mouse macrophages with or without NLRP3 depletion (NLRP3KO, WT). (A) Genes associated with fine determination of macrophage phenotype analyzed by String online tool. (B, C) Gene reads from NLRP3 and some key factors associated with macrophage phenotype and functionality. *p<0.05.