TABLE 1.
Demographic and clinical characteristics of CAD patients and controls.
| All participants (n = 325) | CAD group (n = 182) | Control group (n = 143) | P-value | |
| Age (years) | 49.0 (45.0, 53.0) | 49.0 (45.0, 53.0) | 50.0 (45.0, 54.0) | 0.456 |
| Men [n(%)] | 214 (65.8%) | 151 (83.0%) | 63 (44.1%) | < 0.001 |
| CAD family history [n(%)] | 20 (6.2%) | 9 (4.9%) | 11 (7.7%) | 0.429 |
| Current smokers [n(%)] | 129 (39.7%) | 90 (49.5%) | 39 (27.3%) | 0.0001 |
| HR (beats/minute) | 76.0 (67.0, 86.0) | 76.0 (66.0, 86.0) | 77.0 (70.0, 86.0) | 0.241 |
| Hypertension [n(%)] | 169 (52.0%) | 97 (53.3%) | 72 (50.3%) | 0.677 |
| SBP (mm Hg) | 127.0 (115.0, 144.0) | 126.0 (114.0, 140.0) | 131.0 (116.25, 147.0) | 0.106 |
| DBP (mm Hg) | 82.0 (73.75, 91.0) | 82.0 (72.0, 91.0) | 81.0 (75.0, 91.0) | 0.840 |
| DM [n(%)] | 90 (27.7%) | 59 (32.4%) | 31 (21.7%) | 0.043 |
| FBG (mmol/L) | 5.80 (5.10, 7.44) | 5.93 (5.15, 8.12) | 5.69 (5.05, 6.79) | 0.024 |
| HbA1c (%) | 5.8 (5.4, 6.21) | 5.8 (5.5, 6.4) | 5.7 (5.4, 6.1) | 0.030 |
| HgB (g/L) | 138.0 (125.0, 147.0) | 139.0 (127.0, 147.0) | 133 (121.0, 147.0) | 0.043 |
| TC (mmol/L) | 4.37 (3.71, 5.27) | 4.24 (3.60, 5.23) | 4.51 (3.96, 5.28) | 0.163 |
| LDL-C (mmol/L) | 2.58 (2.06, 3.11) | 2.58 (2.04, 3.28) | 2.56 (2.09, 2.93) | 0.312 |
| HDL-C (mmol/L) | 1.05 (0.87, 1.24) | 0.98 (0.85, 1.19) | 1.13 (0.95, 1.30) | 0.001 |
| TG (mmol/L) | 1.47 (1.07, 2.08) | 1.59 (1.17, 2.34) | 1.35 (0.98, 1.88) | < 0.001 |
| PLT (×10^9/L) | 237.17 ± 66.0 | 243.18 ± 62.90 | 229.53 ± 69.23 | 0.064 |
| ALT (U/L) | 24.0 (18.0, 46.72) | 28.0 (20.0, 94.0) | 22.0 (16.0, 29.0) | < 0.001 |
| AST (U/L) | 28.0 (19.0, 46.0) | 31.84 (21.0, 56.37) | 23.0 (17.0, 34.95) | < 0.001 |
| Scr (μmol/L) | 75.5 (65.80, 89.0) | 76.31 (68.0, 88.4) | 72.58 (61.25, 90.05) | 0.068 |
| AA (μmol/L) | 6.38 (4.31, 8.89) | 7.26 (4.70, 10.23) | 5.91 (3.90, 7.23) | < 0.001 |
| EPA (μmol/L) | 0.58 (0.38, 0.77) | 0.53 (0.37, 0.74) | 0.63 (0.44, 0.80) | 0.017 |
| DHA (μmol/L) | 2.42 (1.58, 3.47) | 2.44 (1.36, 3.60) | 2.37 (1.78, 3.34) | 0.755 |
| EPA/AA | 0.09 (0.07, 0.12) | 0.08 (0.06, 0.10) | 0.11 (0.08, 0.15) | < 0.001 |
| DHA/AA | 0.38 (0.28, 0.51) | 0.35 (0.25, 0.44) | 0.46 (0.33, 0.58) | < 0.001 |
Data are presented as percentages, mean and SD, median and interquartile range. AA, arachidonic acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CAD, coronary artery disease; DBP, diastolic blood pressure; DM, diabetes mellitus; DHA, docosahexaenoic acid; DHA/AA, ratio of DHA and AA; EPA, eicosapentaenoic acid; EPA/AA, ratio of EPA and AA; FBG, fasting blood glucose; HDL-C, high density lipoprotein-cholesterol; HgB, hemoglobin; HR, heart rate; LDL-C, low density lipoprotein-cholesterol; PLT, platelets; SBP, systolic blood pressure; Scr, serum creatinine; TC, total cholesterol; TG, triglyceride.