Table 3.
Cost threshold analysis. Cost threshold analysis for varying specificity of AB-MRI and full protocol breast MRI (FB-MRI). If the cost per examination of AB-MRI was higher than threshold 1, the FB-MRI-strategy would be cost-saving. If the cost per examination of AB-MRI was higher than threshold 2 or threshold 3, FB-MRI would be cost-effective at a willingness-to-pay threshold of $ 50,000 per QALY or $ 100,000 per QALY, respectively. If the cost per examination of AB-MRI was below the second or third threshold-value, AB-MRI should be preferred since FB-MRI would not be cost-effective. The cost thresholds are reported in absolute values in US-$ and in relation to the cost of a FB-MRI examination, which was defined at $ 314 according to Medicare CPT codes
| Specificity of AB-MRI | Specificity of FB-MRI | ||||
|---|---|---|---|---|---|
| 83% | 86% | 89% | 92% | 95% | |
| 81% |
$ 249 (79%), $ 249 (79%), $ 249 (79%) |
$ 246 (78%), $ 244 (78%), $ 242 (77%) |
$ 241 (77%), $ 238 (76%), $ 235 (75%) |
$ 237 (75%), $ 231 (74%), $ 227 (72%) |
$ 232 (74%), $ 225 (72%), $ 219 (70%) |
| 83% | - |
$ 255 (81%), $ 254 (81%), $ 254 (81%) |
$ 250 (80%), $ 248 (79%), $ 246 (78%) |
$ 246 (78%), $ 242 (77%), $ 238 (76%) |
$ 241(77%), $ 236 (75%), $ 231 (74%) |
| 85% | - |
$ 264 (84%), $ 264 (84%), $ 265 (84%) |
$ 260 (83%), $ 258 (82%), $ 257 (82%) |
$ 255 (81%), $ 252 (80%), $ 250 (80%) |
$ 250 (80%), $ 246 (78%), $ 242 (77%) |
| 87% | - | - |
$ 268 (85%), $ 268 (85%), $ 268 (85%) |
$ 265 (84%), $ 262 (83%), $ 261 (83%) |
$ 260 (83%), $ 256 (82%), $ 253 (81%) |
| 89% | - | - | - |
$ 273 (87%), $ 273 (87%), $ 272 (87%) |
$ 270 (86%), $ 266 (85%), $ 264 (84%) |