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. 2022 Nov 3;13:969088. doi: 10.3389/fphar.2022.969088

TABLE 4.

Subgroup analysis.

n HR (95% CI) P P for interaction
2-year all-cause mortality
Heart failure 0.472
Yes 161 0.458 (0.119–1.773) 0.258
No 38 1.264 (0.115–13.948) 0.848
LVEF≤35% 0.968
Yes 25 52.454 (0.000-600986,101) 0.633
No 174 0.492 (0.148–1.634) 0.247
Sex 0.067
male 122 0.696 (0.156–3.111) 0.635
female 77 0.513 (0.094–2.801) 0.441
2-year stroke or heart failure hospitalization
Heart failure 0.581
Yes 161 0.258 (0.073–0.913) 0.036
No 38 0.433 (0.097–1.936) 0.273
LVEF≤35% 0.960
Yes 25 52.454 (0.000-600986,101) 0.633
No 174 0.293 (0.107–0.799) 0.017
Sex 0.209
male 122 0.555 (0.181–1.696) 0.301
female 77 0.123 (0.015–0.988) 0.049
2-year Combined endpoint
Heart failure 0.608
Yes 161 0.384 (0.150–0.982) 0.046
No 38 0.574 (0.143–2.297) 0.432
LVEF≤35% 0.951
Yes 25 54.148 (0.001-5137,804) 0.495
No 174 0.368 (0.162–0.836) 0.017
Sex 0.143
male 122 0.719 (0.284–1.822) 0.487
female 77 0.190 (0.042–0.870) 0.032

Abbreviations: HR, hazard ratio; CI, confidence interval; LVEF: left ventricular eject fraction.