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. 2022 Nov 3;9:951551. doi: 10.3389/fcvm.2022.951551

Table 1.

Summary of sources of data collection, AI/precision medicine and digital divide.

Topics Resources (R) and gaps (G) What's available (A)/What's missing (M)
Need for expanded patient access - Local, state, national, international networks. R.
- Cardiologists and oncologist' collaboration. G.
- Telemedicine, wearables. R.
- Advocacy, education, cardio oncology programs. A.
- Increased community practices involvement. M.
Data collection of clinical information - Electronic health records (EHR). R.
- Prospective registries. R.
- Large clinical trials in cardio oncology. G.
- Clinical, laboratory, imaging, and pharmacy data sharing for clinical and research collaborations. A.
- Observational uniform data collection to evaluate outcomes. A.
Precision medicine - Epigenomics, proteomics, populomics. R.
- Pharmacogenomics, Environmentomics. R.
- Dedicated cancer platforms and cancer LinQ. A.
- AHA: Institute for Precision CV medicine. A.
- Broad utilization in CV medicine. M.
Big data - American College of Cardiology NCDR. R.
- Medicine dataset. R.
- SEER. R.
- Healthcare Cost and Utilization Project (HCUP). R.
- European Health Research and Innovation Cloud. R.
- Complex datasets. A.
- Use of technology to transform data into clinical and research knowledge. A.
- Large prospective datasets. M.
AI/machine learning - Computers AI simulate human intelligence at much higher speeds. R.
- Monitoring risk of cancer treatment related cardiotoxicities. R.
- Established clinical practice. G.
- ML identified cardiotoxicity predictors: troponin, pro BNP, atrial fibrillation, CAD, CHF, CVA. A.
- AI algorithms in echocardiography and imaging for diagnosis, prognosis, and surveillance. A.
Digital divide and health care disparities - Racial minorities higher incidence of cardiotoxicity. G.
- Individuals of lower socioeconomic status have poorer CV outcomes. G.
- At-risk patients in rural areas have limited access to cardio oncology. G.
- Socioeconomic and racial data gaps need to be incorporated into AI/machine learning to ensure adequate representation and equitable solutions. M.

AHA, American Heart Association; CV, cardiovascular; NCDR, National Cardiovascular Data Registry; AI, Artificial Intelligence; SEER, Surveillance, Epidemiology and End Results; ML, Machine learning; BNP, Beta natriuretic peptide; CAD, coronary artery disease; CHF, heart failure; CVA, cerebrovascular accident.