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. 2022 Nov 3;9:1043165. doi: 10.3389/fcvm.2022.1043165

FIGURE 3.

FIGURE 3

Pathway enrichment analysis of upregulated genes involved in osteogenic differentiation of human aortic valve interstitial cells (VIC) by KEGG: biological processes database. Abscissa axis represents biological processes associated with VIC osteogenic differentiation in early timepoint by RNA-seq transcriptomics data (A) or later timepoint by shotgun proteomics data (B); ordinate axis represents number of identified differentially expressed transcripts (A) or proteins (B) enriched in corresponding biological process. Asterisk marked KEGG (*): biological processes enriched in both proteomics and transcriptomics data.