Table 1.

Exposure Characteristics

Category	Term	Definition
Exposure Windows *	Current Use	Exposure within 28 days before the index date (primary analysis)
	Recent Use	Exposure within 84 days before the index date
	Prior Use	Exposure within 85 through 365 days before the index date
	Non-current Use	Cannot have any progestogen exposure within 28 days before the index date (reference for primary analysis)
Dose	Weighted Average Daily Dose	The cumulative prescribed dose within recent use averaged over the interval from start of exposure until the index date (maximum of 84 days)
	Low Category	Weighted average daily dose less than half the standard daily dose of each oral progestogen
	Standard Category	Weighted average daily dose between half to less than double the standard daily dose of each oral progestogen
	High Category	Weighted average daily dose greater than or equal to double the standard daily dose of each oral progestogen
Chronicity	New Users	All exposure occurs within no more than 84 days before the index date (i.e., no prior use) and meets current use criteria
	Chronic Users	Exposure meets both prior use and current use criteria
	Former Users	Exposure meets prior use but not current use criteria
	Non-users	Cannot have any progestogen exposure that meets criteria for current use or prior use (reference only for chronicity analysis)

^*Current, recent, and prior use definitions are not affected by progestogen exposure or absence of exposure outside of its time window (e.g., exposures may continue beyond the index date).