Financial Burden
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Identify High-Risk Populations
Unemployed
Low socioeconomic status
Underinsured or no insurance
Limited English Proficiency
Lower educational attainment
Lower health literacy
Hepatic encephalopathy
Hepatocellular carcinoma
Multimorbidity
Liver transplant candidates/recipients
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Deprescribing
Switching to generic formulations
Discussing lower-cost alternative approaches
Early referral to co-pay and prescription drug assistance programs
Interdisciplinary collaboration with pharmacists
Telehealth and hospital-at-home care models
Transportation and parking vouchers for clinic visits
Early referral of caregivers to local and national support programs
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Financial Distress
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Screen for Financial Distress
Single item: “Are you having difficulty paying for your medical care?”40
American College of Physicians “Costs of Care Conversations” tools and financial screening questions42,43
Comprehensive Score for Financial Toxicity (COST) measure41
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Early referral to social work services
Universal screening for financial distress during clinic visits
Routine costs of care conversations when developing treatment plans
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Financial navigation and assistance programs specific to chronic liver disease
Community health workers and patient navigators to maximize social support
Comparative effectiveness and cost effectiveness studies in hepatology to inform practice guidance
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