Table 2.

Meningioma: molecular alterations associated with specific morphologies, anatomic locations and grades

Meningioma molecular alteration associated with specific morphology or location
SMARCE1 mutation	Clear cell meningioma
BAP1 mutation or deletion	Rhabdoid meningioma
22q deletion and/or NF2 mutation	Convexity and (majority) of spinal meningiomas
AKT1, TRAF7, SMO and/or PIK3CA mutations	Skull base meningioma
Molecular alterations warranting WHO grade 3 designation (regardless of morphologic features)
TERT promoter mutation
Homozygous deletion of CDKN2A and/or CDKN2B