Table 3:
Differences in reported history of paternal and maternal parkinsonism between PD groups
Parkinsonism in parent N (%) | Parkinsonism in mother N (%) | Parkinsonism in father N (%) | p | |
---|---|---|---|---|
Idiopathic PD | 61/420 (14.5%) | 19/61 (31.2%) | 43/61 (70.5%) | 0.002 |
LRRK2 PD | 30/99 (30.3%) | 16/30 (53.3%) | 16/30 (53.3%) | 1 |
GBA PD | 14/107 (13.1%) | 5/14 (35.7%) | 9/14 (64.3%) | 0.268 |
LRRK2 GBA PD | 3/10 (30.3%) | 2/3 (66.7%) | 1/3 (33.3%) | 0.531 |
While idiopathic PD were more likely to report a history of parkinsonism in a father (43/61, 70.5%) compared to a mother (19/61, 31.2%) (p=0.002), there was no difference in maternal or paternal risk of parkinsonism among LRRK2 PD or GBA PD