Skip to main content
. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Thromb Haemost. 2022 Oct 11;20(12):2873–2886. doi: 10.1111/jth.15877

Figure 2. Gene expression of inflammatory markers are reduced in eWAT of HFD-fed Fibγ390-396A and FXIII- mice, but not of Fib- and FibAEK mice.

Figure 2.

(A-C) Levels of mRNA encoding (A) F4/80 (Adgre1), (B) MCP-1 (Ccl2) and (C) Tnfα (Tnfa) in eWAT of FibγWT and Fibγ390-396A mice. (D-F) Levels of mRNA encoding (D) Adgre1, (E) Ccl2 and (F) Tnfa in eWAT of Fib+ and Fib- mice. (G-I) Levels of mRNA encoding (G) Adgre1, (H) Ccl2 and (I) Tnfa in eWAT of FibWT and FibAEK mice. (J-L) Levels of mRNA encoding (J) Adgre1, (K) Ccl2 and (L) Tnfa in eWAT of FXIII+ and FXIII- mice. Data are expressed as mean±SEM and analyzed by 2-way ANOVA with Fisher’s LSD test. *P<0.05, **P<0.01, ***P<0.001. LFD: n=3–7; HFD: n=6–10