Skip to main content
. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Thromb Haemost. 2022 Oct 11;20(12):2873–2886. doi: 10.1111/jth.15877

Figure 4. Gene expression of inflammatory markers and lipid metabolism in livers of HFD-fed Fibγ390-396A Fib-, FibAEK and FXIII- mice.

Figure 4.

(A-F) Levels of mRNA encoding the genes (A) F4/80 (Adgre1), (B) MCP-1 (Ccl2), (C) Tnfα (Tnfa), (D) Pparγ (Pparg), (E) Cidea (Cidea) and (F) CD36 (Cd36) in livers of FibγWT and Fibγ390-396A mice. (G-L) Levels of mRNA encoding the genes (G) Adgre1, (H) Ccl2, (I) Tnfa, (J) Pparg, (K) Cidea and (L) Cd36 in livers of Fib+ and Fib- mice. (M-R) Levels of mRNA encoding the genes (M) Adgre1, (N) Ccl2, (O) Tnfa, (P) Pparg, (Q) Cidea and (R) Cd36 in livers of FibWT and FibAEK mice. (S-X) Levels of mRNA encoding the genes (S) Adgre1, (T) Ccl2), (U) Tnfa, (V) Pparg, (W) Cidea and (X) Cd36 in livers of FXIII+ and FXIII- mice. Data are expressed as mean±SEM and analyzed by 2-way ANOVA with Fisher’s LSD test. *P<0.05, **P<0.01, ***P<0.001. LFD: n=4–7; HFD: n=6–12