(A-C) Circulating levels of (A) total cholesterol, (B) high-density lipoprotein (HDL)-cholesterol and (C) free cholesterol in FibγWT and Fibγ390-396A mice. (D-F) Circulating levels of (D) total cholesterol, (E) HDL-cholesterol and (F) free cholesterol in Fib+ and Fib- mice. (G-I) Circulating levels of (G) total cholesterol, (H) HDL-cholesterol and (I) free cholesterol in FibWT and FibAEK mice. (J-L) Circulating levels of (J) total cholesterol, (K) HDL-cholesterol and (L) free cholesterol in FXIII+ and FXIII- mice. (V-X) Data are expressed as mean±SEM and analyzed by 2-way ANOVA with Fisher’s LSD test. *P<0.05, **P<0.01, ***P<0.001. LFD: n=4–7; HFD: n=6–12