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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Eur J Haematol. 2022 Oct 4;109(6):633–642. doi: 10.1111/ejh.13870

Table 1.

Characteristics of different oral iron formulations.

Formulations Benefits Complications
Ferrous Iron Salts * Inexpensive, widely available Tendency to cause gastrointestinal side effects
Polysaccharide-Iron Complex Potentially lower risk of gastrointestinal intolerance, better taste profile Less effective than ferrous salts in at least one randomized clinical trial of children.
Heme Iron Higher absorption rate Expensive. Not be a viable option for vegetarian or vegan individuals.
Carbonyl Iron Inexpensive No clear efficacy or side effect benefit as compared
Iron Protein Succinylate Some data to suggest there may be better tolerability and efficacy as compared to ferrous salts. Unsuitable for individuals with hypersensitivity to milk protein
Iron Amino Acid Chelates ** Less susceptible to dietary interactions. May be more expensive than ferrous salts
*

Ferrous sulfate, Ferrous fumarate, Ferrous gluconate

**

Ferrous Bisglycinate, Ferric Trisglycinate