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. Author manuscript; available in PMC: 2023 May 14.
Published in final edited form as: Clin Cancer Res. 2022 Nov 14;28(22):4907–4916. doi: 10.1158/1078-0432.CCR-22-1547

Figure 2. Integrated immunoPET, IHC, and H&E images of tumorgraft (TG) lines and the corresponding patient tumors.

Figure 2.

Top panel: Representative whole body maximal intensity projection immunoPET images (posterior view) of mice, one from each group of mice bearing one of the 7 RCC TG lines. Shown below are the corresponding PD-L1 expression range measured by IHC and the volume of the tumor in the mouse (n = 3 – 4 for each line; a single remaining XP258 mouse not included). Tumors are indicated with a yellow lasso. Bottom panel: PD-L1 IHC and hematoxylin and eosin (H&E) staining of the corresponding tumor tissues explanted from the TG models. Patient tumor samples shown as a reference.