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. Author manuscript; available in PMC: 2023 Nov 11.
Published in final edited form as: Circ Res. 2022 Oct 20;131(11):e152–e168. doi: 10.1161/CIRCRESAHA.120.318102

Fig. 4. Lineage selective GATA4 regions and lineage selective chromatin accessibility.

Fig. 4.

A. Schematic for measuring lineage-selective chromatin accessibility using ATAC-seq. E12.5 ECs and CMs were isolated and chromatin accessibility was measured by ATAC-seq. Heatmap shows Spearman correlation between EC and CM ATAC-seq data across the union of identified peaks. B. Lineage-selective GATA4 regions and lineage-selective chromatin accessibility. Each row represents a GATA4 region, and the color intensity indicates ChIP-seq or ATAC-seq signal. C. ATAC-seq signal at GATA4 regions. EC- and CM- selective GATA4 regions were accessible in the concordant lineage. D,E. Representative browser views showing lineage selective GATA4 and ATAC-seq data.