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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: J Physiol. 2022 Oct 5;600(22):4779–4806. doi: 10.1113/JP283319

Table 4.

Intra-class correlation coefficients (ICC), and Bland-Altman results between dP/dtmax-EDV(IVC) obtained from inferior vena cava (IVC) occlusion and other single-beat surrogate metrics calculated from beat-by-beat baseline pressure-volume and arterial recordings in rats (n = 30).

ICC Bland-Altman, 95% LOA

ICC Size 95% CI P Lower Upper
dP/dtmax-EDV(IVC) vs. single-beat surrogates of dP/dtmax-EDV(IVC)

  LVdP/dtmax-EDV 0.700* Moderate −0.213–0.907 < 0.001 −46.584 5.876
  ARTdP/dtmax-EDV 0.758* Good 0.486–0.885 < 0.001 −44.93 28.184
  Pmax-EDV 0.845* Good 0.673–0.927 < 0.001 −1.452 1.452
  LVESP-EDV 0.853* Good 0.689–0.930 < 0.001 −1.421 1.421
  ARTESP-EDV 0.822* Good 0.624–0.916 < 0.001 −1.54 1.54

dP/dtmax-EDV(IVC) vs. other single-beat surrogates of cardiac contractility

  Ees(SB1) 0.344 - −0.414–0.691 0.138 −2.475 2.475
  Ees(SB2) 0.313 - −0.482–0.677 0.166 −2.509 2.509
  PRSW(SB) 0.413 - −0.262–0.723 0.084 −2.394 2.394
  PWRmax-EDV 0.437 - −0.210–0.735 0.069 −2.364 2.364
  PRWmax-EDV2 0.691* Moderate 0.343–0.854 0.001 −1.921 1.921
  LVEFEA1 0.782* Good 0.539–0.897 < 0.001 −1.675 1.675
  LVEFEA2 0.743* Moderate 0.455–0.878 < 0.001 −1.789 1.789

dP/dtmax-EDV(IVC) vs. load-dependent metrics

  LVdP/dtmax 0.612* Moderate 0.173–0.817 0.008 −2.087 2.087
  ARTdP/dtmax 0.483* Poor −0.107–0.756 0.044 −2.3 2.3
  Pmax 0.217 - −0.696–0.632 0.263 −2.603 2.603
  LVESP 0.200 - −0.734–0.624 0.282 −2.618 2.618
  ARTESP (0.9 × SBP) 0.061 - −1.046–0.560 0.436 −2.729 2.729
  PWRmax −0.206 - −1.656–0.438 0.685 −2.894 2.894
  SW −2.912 - −8.653−−0.739 0.999 −3.464 3.464

dP/dtmax-EDV(IVC), the relation between the maximal rate of rise of pressure and end-diastolic volume (EDV) obtained from IVC occlusion; LVdP/dtmax-EDV, the maximal rate of rise of the left ventricular pressure (LVdP/dtmax) and EDV ratio; ARTdP/dtmax-EDV, the maximal rate of rise of the arterial pressure (ARTdP/dtmax) and EDV ratio; Pmax-EDV, maximal pressure (Pmax) and EDV ratio; LVESP-EDV, LV end-systolic pressure (LVESP) and EDV ratio, ARTESP-EDV, Arterial ESP (ARTESP, 0.9 × systolic blood pressure (SBP) and EDV ratio; Ees(SB1), LVESP and end-systolic volume (ESV) ratio; Ees(SB2), ARTESP and ESV ratio; PRSW(SB), stroke work (SW) and EDV ratio; PWRmax-EDV, power max (PWRmax) and EDV ratio; PWRmax-EDV2, PWRmax and squared of EDV ratio; LVEFEA1, afterload adjusted left ventricular ejection fraction using ventricular data; LVEFEA2, afterload adjusted left ventricular ejection fraction using arterial data; LOA, limit of agreement.

*

significant observation