Table 4.
Intra-class correlation coefficients (ICC), and Bland-Altman results between dP/dtmax-EDV(IVC) obtained from inferior vena cava (IVC) occlusion and other single-beat surrogate metrics calculated from beat-by-beat baseline pressure-volume and arterial recordings in rats (n = 30).
| ICC | Bland-Altman, 95% LOA | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| ICC | Size | 95% CI | P | Lower | Upper | |
| dP/dtmax-EDV(IVC) vs. single-beat surrogates of dP/dtmax-EDV(IVC) | ||||||
|
| ||||||
| LVdP/dtmax-EDV | 0.700* | Moderate | −0.213–0.907 | < 0.001 | −46.584 | 5.876 |
| ARTdP/dtmax-EDV | 0.758* | Good | 0.486–0.885 | < 0.001 | −44.93 | 28.184 |
| Pmax-EDV | 0.845* | Good | 0.673–0.927 | < 0.001 | −1.452 | 1.452 |
| LVESP-EDV | 0.853* | Good | 0.689–0.930 | < 0.001 | −1.421 | 1.421 |
| ARTESP-EDV | 0.822* | Good | 0.624–0.916 | < 0.001 | −1.54 | 1.54 |
|
| ||||||
| dP/dtmax-EDV(IVC) vs. other single-beat surrogates of cardiac contractility | ||||||
|
| ||||||
| Ees(SB1) | 0.344 | - | −0.414–0.691 | 0.138 | −2.475 | 2.475 |
| Ees(SB2) | 0.313 | - | −0.482–0.677 | 0.166 | −2.509 | 2.509 |
| PRSW(SB) | 0.413 | - | −0.262–0.723 | 0.084 | −2.394 | 2.394 |
| PWRmax-EDV | 0.437 | - | −0.210–0.735 | 0.069 | −2.364 | 2.364 |
| PRWmax-EDV2 | 0.691* | Moderate | 0.343–0.854 | 0.001 | −1.921 | 1.921 |
| LVEFEA1 | 0.782* | Good | 0.539–0.897 | < 0.001 | −1.675 | 1.675 |
| LVEFEA2 | 0.743* | Moderate | 0.455–0.878 | < 0.001 | −1.789 | 1.789 |
|
| ||||||
| dP/dtmax-EDV(IVC) vs. load-dependent metrics | ||||||
|
| ||||||
| LVdP/dtmax | 0.612* | Moderate | 0.173–0.817 | 0.008 | −2.087 | 2.087 |
| ARTdP/dtmax | 0.483* | Poor | −0.107–0.756 | 0.044 | −2.3 | 2.3 |
| Pmax | 0.217 | - | −0.696–0.632 | 0.263 | −2.603 | 2.603 |
| LVESP | 0.200 | - | −0.734–0.624 | 0.282 | −2.618 | 2.618 |
| ARTESP (0.9 × SBP) | 0.061 | - | −1.046–0.560 | 0.436 | −2.729 | 2.729 |
| PWRmax | −0.206 | - | −1.656–0.438 | 0.685 | −2.894 | 2.894 |
| SW | −2.912 | - | −8.653−−0.739 | 0.999 | −3.464 | 3.464 |
dP/dtmax-EDV(IVC), the relation between the maximal rate of rise of pressure and end-diastolic volume (EDV) obtained from IVC occlusion; LVdP/dtmax-EDV, the maximal rate of rise of the left ventricular pressure (LVdP/dtmax) and EDV ratio; ARTdP/dtmax-EDV, the maximal rate of rise of the arterial pressure (ARTdP/dtmax) and EDV ratio; Pmax-EDV, maximal pressure (Pmax) and EDV ratio; LVESP-EDV, LV end-systolic pressure (LVESP) and EDV ratio, ARTESP-EDV, Arterial ESP (ARTESP, 0.9 × systolic blood pressure (SBP) and EDV ratio; Ees(SB1), LVESP and end-systolic volume (ESV) ratio; Ees(SB2), ARTESP and ESV ratio; PRSW(SB), stroke work (SW) and EDV ratio; PWRmax-EDV, power max (PWRmax) and EDV ratio; PWRmax-EDV2, PWRmax and squared of EDV ratio; LVEFEA1, afterload adjusted left ventricular ejection fraction using ventricular data; LVEFEA2, afterload adjusted left ventricular ejection fraction using arterial data; LOA, limit of agreement.
significant observation