Table 1.
The anthropometry characteristics of the four AIM subgroups of obesity patients at baseline and 12-month post-surgery.
| MHO | HMO-U | HMO-I | LMO | p value& | |
|---|---|---|---|---|---|
| N | 377 | 327 | 42 | 262 | |
| Man/Woman (woman %) | 150/227 (60.2%) | 134/193 (59.0%) | 25/17 (40.5%) | 120/142 (54.2%) | 0.055 |
| Age (years) | 31 (25,37) | 28 (23,34) | 27 (20,32) | 37 (30,46) | <0.0001 |
| Obesity duration (years) | 10.0 (5.0,16.3) | 10.0 (5.0,18.0) | 10.0 (5.0,17.0) | 15.0 (9.0,20.8) | <0.0001 |
| Type of surgery (RYGB%) | 17.0% | 13.1% | 9.5% | 37.0% | <0.0001 |
| Rate of diabetes (%) | 33.2% | 32.1% | 9.5% | 99.2% | <0.0001 |
| Diabetes duration (years) | 0.5 (0,2.5) | 0 (0,1.0) | 0 (0,0.1) | 1.0 (0,5.0) | <0.0001 |
| Weight (kg) | |||||
| Baseline | 103.5 (90.0, 124.6) | 113.4 (98.3, 130.0) | 116.6 (101.7, 129.7) | 100.0 (86.0, 120.1) | <0.0001 |
| 12 months | 74.1 (64.1, 87.3) # | 78.4 (66.9, 89.1) # | 80.2 (71.1, 95.9) # | 71.7 (62.1, 83.2) # | 0.354 |
| Absolute change | -31.6 (-41.8, -23.7) | -37.8 (-47.2, -31.3) | -37.4 (-53.8, -31.9) | -24.6 (-31.8, -17.1) | <0.0001 |
| Percent change (%) | -29.4% (-35.7%, -25.0%) | -33.5% (-38.3%, -26.9%) | -34.0% (-37.6%, -25.0%) | -24.4% (-30.2%, -20.3%) | <0.0001 |
| BMI (kg/m2) | |||||
| Baseline | 37.2 (33.3, 41.6) | 39.2 (35.4, 44.0) | 39.2 (36.3, 41.8) | 36.4 (31.5, 41.0) | <0.0001 |
| 12 months | 26.9 (23.5, 30.1) # | 27.0 (24.5, 30.3) # | 27.1 (24.7, 29.1) # | 26.7 (23.3, 29.4) # | 0.781 |
| Absolute change | -11.1 (-13.9, -9.2) | -13.3 (-16.3, -10.8) | -12.5 (-16.2, -9.2) | -8.9 (-11.3, -6.4) | <0.0001 |
| Percent change (%) | -29.4% (-35.7%, -25.0%) | -33.5% (-38.3%, -26.9%) | -34.0% (-37.6%, -25.0%) | -24.4% (-30.2%, -20.3%) | <0.0001 |
| Excess weight (kg) | |||||
| Baseline | 37.9 (25.3, 52.3) | 45.3 (31.8, 58.4) | 43.1 (34.8, 55.2) | 33.8 (21.1, 49.3) | <0.0001 |
| 12 months | 8.1 (-1.3, 17.4) # | 8.2 (1.4, 17.0) # | 10.3 (1.9, 16.9) # | 7.2 (-2.1, 15.9) # | 0.696 |
| Absolute change | -31.6 (-41.8, -23.7) | -37.8 (-47.2, -31.3) | -37.4 (-53.8, -31.9) | -24.6 (-31.8, -17.1) | <0.0001 |
| Percent change (%) | -81.1% (-105.6%, -66.2%) | -83.1% (-96.6%, -68.7%) | -79.3% (-95.8%, -65.9%) | -77.7% (-111.8%, -62.0%) | 0.756 |
| WC (cm) | |||||
| Baseline | 115 (106, 129) | 120 (109, 130) | 120 (111, 130) | 116 (105, 128) | 0.011 |
| 12 months | 89 (82, 101) # | 92 (85, 98) # | 90 (84, 96) # | 92 (83, 98) # | 0.885 |
| Absolute change | -27 (-35, -19) | -31 (-35, -23) | -30 (-46, -26) | -21 (-29, -14) | <0.0001 |
| Percent change (%) | -22.8% (-28.6%, -16.6%) | -23.9% (-29.9%, -19.5%) | -26.7% (-30.9%, -22.0%) | -18.2% (-23.7%, -14.8%) | <0.0001 |
| HC (cm) | |||||
| Baseline | 120 (112, 129) | 124 (114, 132) | 120 (113, 132) | 115 (107, 125) | <0.0001 |
| 12 months | 101 (95, 106) # | 100 (94, 107) # | 103 (98, 107) # | 98 (91, 105) # | 0.486 |
| Absolute change | -20 (-25, -13) | -23 (-28, -16) | -19 (-33, -11) | -13 (-19, -8) | <0.0001 |
| Percent change (%) | -16.0% (-19.7%, -11.6%) | -18.3% (-21.6%, -12.7%) | -15.3% (-22.7%, -9.5%) | -11.6% (-15.0%, -7.7%) | <0.0001 |
| WHR (ratio) | |||||
| Baseline | 0.98 (0.91, 1.02) | 0.97 (0.93, 1.03) | 1.02 (0.96, 1.07) | 1.00 (0.96, 1.04) | 0.006 |
| 12 months | 0.91 (0.85, 0.95) # | 0.90 (0.87, 0.95) # | 0.88 (0.83, 0.93) # | 0.92 (0.88, 0.97) # | 0.065 |
| Absolute change | -0.08 (-0.12, -0.03) | -0.08 (-0.13, -0.04) | -0.13 (-0.18, -0.10) | -0.07 (-0.10, -0.04) | 0.065 |
| Percent change (%) | -8.2% (-11.8%, -3.7%) | -8.3% (-12.2%, -3.9%) | -12.8% (-16.8%, -10.8%) | -6.7% (-10.4%, -4.1%) | 0.062 |
Values are shown as ratio or median (IQR 25-75%), and analysis were adjusted for sex and age (except analysis for sex and age). MHO, metabolic healthy obesity; HMO-U, hypermetabolic obesity-hyperuricemia subtype; HMO-I, hypermetabolic obesity-hyperinsulinemia subtype; LMO, hypometabolic obesity; BMI, body mass index; WC, waist circumference; HC, hip circumference; WHR, Waist-to-Hip Ratio. #P< 0.01 vs. baseline; & the overall ANCOVA p values.