TABLE 2.
Primary and secondary outcome results
| Control | F ENO | OR (95% CI) FENO versus control | Coefficient (95% CI) FENO–control | p-value | |
| Infant outcome | (n=608) | (n=615) | |||
| Adverse perinatal outcome (primary) | 152/594 (25.6) | 177/603 (29.4) | 1.21 (0.94–1.56) | 0.15 | |
| Preterm birth | 54/597 (9.0) | 62/606 (10.2) | 1.14 (0.78–1.68) | 0.50 | |
| Small for gestational age | 87/596 (14.6) | 93/603 (15.4) | 1.06 (0.77–1.46) | 0.70 | |
| Perinatal mortality | 1/597 (0.2) | 5/605 (0.8) | 3.62 (0.80–16.5) | 0.10 | |
| Neonatal hospitalisation at birth | 76/595 (12.8) | 92/601 (15.3) | 1.24 (0.89–1.72) | 0.21 | |
| Birthweight, g | 3322.3±603.9 | 3309.6±623.9 | −11.2 (−79.8–57.5) | 0.75 | |
| Maternal outcome | (n=599) | (n=601) | |||
| Maternal hospitalisation for asthma exacerbation | 6/543 (1.1) | 6/554 (1.1) | 1.02 (0.32–3.20) | 0.98 | |
| Maternal hospitalisation/ED presentation | 25/543 (4.6) | 30/554 (5.4) | 1.19 (0.69–2.05) | 0.54 | |
| Maternal exacerbations requiring intervention | 104/543 (19.2) | 89/554 (16.1) | 0.80 (0.58–1.10) | 0.17 |
Data are presented as n, n/N (%) or mean±sd, unless otherwise stated. FENO: fractional exhaled nitric oxide; ED: emergency department.