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. 2022 Nov 3;16:996325. doi: 10.3389/fnins.2022.996325

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Copyright © 2022 Wang, Zheng, Yang, Chen, Li, Chen, Hu, Cao, Ren, Qin, Yang, Lu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased FC between M1 subregions and the whole brain in ICCI patients. Compared with HCs, ICCI patients demonstrated decreased FC in bilateral LG, left FG and right PSMC when the seed was located in the left A4hf, as well as decreased FC in bilateral FG and left PSMC when the seed was located in the right A4hf. Moreover, ICCI patients showed decreased FC between the left A6cdl and right LG, left CG, as well as decreased FC between the right A6cdl and right FG. In addition, decreased FC between the left A4ul and bilateral FG, right PSMC as well as decreased FC between the right A4ul and left LG, PSMC, right FG was also found in ICCI patients. Besides, when the seed was located in the left A4t, ICCI patients demonstrated decreased FC in right TP, LG and left FG [corrected at cluster level with family wise error (FWE) P < 0.05 and cluster size > 75]. FC, functional connectivity; M1, primary motor cortex; ICCI, incomplete cervical cord injury; HCs, healthy controls; LG, lingual gyrus; FG, fusiform gyrus; PSMC, primary sensorimotor cortex; CG, calcarine gyrus; TP, temporal pole.