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. 2022 Nov 3;14:1018071. doi: 10.3389/fnagi.2022.1018071

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Copyright © 2022 Nelson, Veal, Andel, Martinkova, Veverova, Horakova, Nedelska, Laczó, Vyhnalek and Hort.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plots of significant moderations by education of the associations between brain volume and cognition for women with dementia. High education corresponds to 1 SD above the mean and low education corresponds to 1 SD below the mean. The red dotted line represents high education, and the blue solid line represents low education. Shaded areas represent 95% confidence intervals. Cognition and brain volume were standardized. (A) Significant negative association between hippocampal volume and attention/working memory for participants with high education; non-significant positive association for low education. (B) Non-significant negative association between total gray matter volume and attention/working memory for participants with high education; significant positive association for low education. (C) Significant negative association between hippocampal volume and executive control for participants with high education; non-significant positive association for low education. (D) Non-significant negative association between total gray matter volume and visuospatial skills for participants with high education; significant positive association for low education.