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. 2022 Nov 3;10:995732. doi: 10.3389/fcell.2022.995732

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Copyright © 2022 Xu, Zhou, Zhan, Bi and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment based on Mfuzz clustering by three GO annotations. (A–C) Three GO annotated heatmaps of proteins were obtained: (A) BP, (B) CC, and (C) MF, with altered expression levels among the six Mfuzz clustering groups. The heatmap scale is based on Z scores ranging from −2/−1 (blue) to 1/2 (red), with a midpoint of 0 (white). (D–F) GO-based enrichment analysis is divided into cluster 1 (D), cluster 4 (E), and cluster 3 (F). The BP, CC, and MF are labeled in green, orange, and blue, respectively.