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(A) Volcano plot showing differentially expressed genes of collagen biosynthesis, extracellular matrix biosynthesis and degradation, TGF-β and Hippo pathways. (B) Validation by qRT-PCR. T-test: AMOTL1 p = 0.031, COL3A1 p = 0.00028, CXCL12 p = 3.9 e-05, LOX p = 0.027, SLUG (SNAI2) p = 0.0052, SMAD3 p = 0.014, SPP1 p = 0.00083, TGFB1 p = 0.043, TGFBR2 p = 0.029, TJP1 p = 0.072. QRT-PCR units: ΔΔCt.
