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(A) Established area of mature fibrosis (HE). Scale bar: 100 μm. (B) Lack of expression of SPARC in mature fibrosis in contrast to moderate SPARC expression in an active proliferative area (inset). Scale bar: 100 μm. (C,D). Lack of CTHRC1 expression (C) and diminished α-muscle actin expression (D) in the same fibrotic area. Scale bar: 100 μm.
