TABLE 2.
Overview of the small-molecule drugs and m6A-related factor inhibitors described in the text.
Drug/inhibitor | Molecular structure | m6A proteins involved | Function | References |
---|---|---|---|---|
SAM mimic |
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METTL3 | METTL3 inhibitor | Bedi et al. (2020) |
UZH1a |
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METTL3 | METTL3 inhibitor | Moroz-Omori et al. (2021) |
Rhein |
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FTO | FTO inhibitor | Li Q. et al. (2016) |
Fluorescein derivative |
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FTO | FTO inhibitor | Wang et al. (2015) |
Radicicol |
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FTO | FTO inhibitor | Wang R. et al. (2018) |
Meclofenamic acid (MA) |
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FTO | FTO inhibitor | Huang et al. (2015) |
CHTB |
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FTO | FTO inhibitor | Qiao et al. (2016) |
Entacapone |
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FTO | FTO inhibitor | Peng et al. (2019) |
N-CDPCB |
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FTO | FTO inhibitor | Qiao et al. (2017) |
Dac51 |
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FTO | FTO inhibitor | Liu et al. (2021) |
MV1035 |
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ALKBH5 | ALKBH5 inhibitor | Malacrida et al. (2020) |