Table 4.
Hazard ratio of MACE by subgroups.
| Among PS matched cohort | MACE | MI | Ischemic stroke | CVD death | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n = 44,616) | n | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | ||||
| Male (n = 18,549) |
1,241 | 0.95 | 0.85 | 1.06 | 1.53 | 1.23 | 1.90 | 0.84 | 0.73 | 0.95 | 0.90 | 0.59 | 1.36 |
| Female (n = 26,067) |
1,383 | 0.87 | 0.79 | 0.97 | 0.96 | 0.72 | 1.28 | 0.86 | 0.77 | 0.97 | 0.93 | 0.56 | 1.54 |
| Age < 65 years (n = 29,774) |
1,040 | 1.13 | 1.00 | 1.28 | 1.50 | 1.16 | 1.93 | 1.08 | 0.94 | 1.24 | 1.16 | 0.65 | 2.07 |
| Age ≥65 years (n = 14,842) |
1,584 | 0.87 | 0.78 | 0.96 | 1.18 | 0.92 | 1.51 | 0.82 | 0.74 | 0.92 | 0.92 | 0.62 | 1.35 |
| No Diabetes mellitus (n = 24,265) |
1,127 | 1.03 | 0.91 | 1.15 | 1.48 | 1.12 | 1.95 | 0.96 | 0.84 | 1.09 | 1.09 | 0.62 | 1.91 |
| Diabetes mellitus (n = 20,351) |
1,497 | 0.82 | 0.74 | 0.90 | 1.15 | 0.92 | 1.43 | 0.77 | 0.69 | 0.87 | 0.82 | 0.55 | 1.21 |
| No Hypertension (n = 10,067) |
299 | 1.44 | 1.14 | 1.82 | 1.82 | 1.07 | 3.08 | 1.39 | 1.07 | 1.80 | 1.35 | 0.43 | 4.25 |
| Hypertension (n = 34,549) |
2,325 | 0.87 | 0.80 | 0.94 | 1.23 | 1.02 | 1.48 | 0.81 | 0.74 | 0.89 | 0.89 | 0.64 | 1.24 |
Hazard ratio (HR) was obtained with reference to the statin non-user group. CVD, cardiovascular disease; MACE, major adverse cardiovascular events, MI, myocardial infarction; CI, confidence interval.