Table 2.
Baseline characteristics at hospital admission (matched groups)
|
Characteristics
|
No TIPS
|
TIPS
|
P
value
|
| Patients | 214 | 214 | |
| Male | 142 (66%) | 153 (71%) | 0.30 |
| Age (yr) | 59.4 (26.4-93.4) | 59.1 (29.9-80.7) | 0.14 |
| Cause of cirrhosis | 0.26 | ||
| -Alcohol | 163 (76%) | 179 (84%) | |
| -Viral hepatitis | 8 (4%) | 4 (2%) | |
| -Other | 43 (20%) | 31 (14%) | |
| Child points (min-max) | 9 (7-14) | 9 (7-14) | 0.76 |
| Hepatic encephalopathy (west-haven) | 0.65 | ||
| -None | 173 (81%) | 165 (77%) | |
| -Grade 1-2 | 22 (10%) | 30 (14%) | |
| -Grade 3-4 | 19 (9%) | 19 (9%) | |
| ACLF grade at hospital admission | 0.37 | ||
| -No ACLF | 176 (82%) | 173 (81%) | |
| -AACLF 1 | 36 (17%) | 39 (18%) | |
| -ACLF 2 | 2 (1%) | 1 (0.5%) | |
| -ACLF 3 | 0 (0%) | 1 (0.5%) | |
| Laboratory findings | |||
| -Meld | 14 (7-36) | 14 (7-40) | 0.97 |
| -Total bilirubin (μmol/L) | 29.7 (5.9-261.0) | 28.1 (6.1-688.5) | 0.10 |
| -Creatinine (μmol/L) | 90.9 (23.1-781.0) | 107.0 (42.3-783.5) | 0.08 |
| -INR | 1.32 (0.92-2.41) | 1.28 (0.97-2.50) | 0.28 |
| -Sodium (mmol/L) | 135 (106-144) | 133 (115-146) | 0.10 |
| -Albumin (g/L) | 24.3 (7.9-48.7); NA: 27 | 26.1 (11.0-39.6); NA: 23 | 0.61 |
| -CRP (mg/L) | 18.7 (1.0-283.0) | 18.0 (2.0-181.0) | 0.10 |
| -Hemoglobin (mmol/L) | 6.8 (2.1-9.8) | 6.7 (3.4-10.0) | 0.43 |
| -Platelets (Gpt/L) | 141.0 (23.0-715.0) | 154.0 (13.0-668.0) | 0.08 |
| -Leucocytes (Gpt/L) | 7.58 (1.34-44.90) | 7.34 (2.72-33.20) | 0.98 |
Continuous variables are given as median and range, categorical variables as total number and percentage. Continuous variables were compared using Wilcoxon signed-rank test and categorical variables using McNemar-Test. NA: Not available; ACLF: Acute on chronic liver failure; TIPS: Transjugular intrahepatic portosystemic shunt.