Table 2.
Clinical outcomes.
| All patients (n = 438) | 00:00–06:00 (n = 58) | 06:00–12:00 (n = 151) | 12:00–18:00 (n = 134) | 18:00–24:00 (n = 95) | p | 95% CI | Adjusted OR, (95% CI) | Adjusted p | |
|---|---|---|---|---|---|---|---|---|---|
| Efficacy outcomes | |||||||||
| 3-month mRS, Mean ± SD | 3.3 (±1.93) | 2.69 (±1.91) | 3.17 (±1.94) | 3.46 (±1.93) | 3.67 (±1.83) | 0.012 | NA | NA | 0.007a |
| 3-month mRS 0–2, n (%) | 178 (40.6%) | 34 (58.6%) | 66 (43.7%) | 49 (36.6%) | 29 (30.5%) | 0.004 | 2.63–2.86 | 0.611 (0.404–0.925)a | 0.020a |
| 3-month mortality, n (%) | 90 (20.8%) | 8 (13.8%) | 32 (21.2%) | 25 (19.1%) | 25 (27.2%) | 0.237 | 2.54–2.95 | 1.060 (0.627–1.791)a | 0.829a |
| Safety outcome | |||||||||
| Symptomatic ICH, n (%) | 40 (9.1%) | 1 (1.7%) | 18 (11.9%) | 14 (10.4%) | 8 (8.4%) | 0.142 | 2.45–2.96 | 0.684 (0.335–1.394)b | 0.296b |
| Early recanalization | |||||||||
| TICI ≥2b, n (%) | 376(86.2%) | 44 (75.9%) | 130 (86.1%) | 119 (90.2%) | 83 (87.4%) | 0.07 | 1.87–2.16 | 1.812 (0.944–3.479)c | 0.074c |
Data are displayed as n%, or mean(± SD); SD: standard deviation; OR: odds ratio; CI: confidence interval; TICI: thrombolysis in cerebral infarction; ICH: intracerebral hemorrhage; mRS: modified Rankin scale.
aAdjusted for NIHSS on admission, intravenous rt-PA, TICI scores, onset to groin puncture, onset to recanalization, gender, age, hypertention, hyperlipidemia, diabetes mellitus, atrial fibrillation, previous stroke, sICH.
bAdjusted for NIHSS on admission, intravenous rt-PA, TICI scores, onset to groin puncture, onset to recanalization, gender, age, hypertention, hyperlipidemia, diabetes mellitus, atrial fibrillation, previous stroke.
cAdjusted for NIHSS on admission, intravenous rt-PA, onset to groin puncture, onset to recanalization, gender, age, hypertention, hyperlipidemia, diabetes mellitus, atrial fibrillation, previous stroke, sICH.