A Body weight in CON (n = 11), DAT (n = 8) and TH (n = 23) male mice. B Daily food intake in CON (n = 10), DAT (n = 8) and TH (n = 11) male mice. C Oxygen consumption in CON (n = 17), DAT (n = 8) and TH (n = 10) male mice. D Ambulatory activity in CON (n = 17), DAT (n = 8) and TH (n = 10) male mice. E Respiratory exchange ratio (RER) in CON (n = 17), DAT (n = 8) and TH (n = 10) male mice. F Body weight in CON (n = 44), DAT (n = 8) and TH (n = 20) female mice. G Daily food intake in CON (n = 27), DAT (n = 9) and TH (n = 9) female mice. H Oxygen consumption in CON (n = 14), DAT (n = 8) and TH (n = 8) female mice. I Ambulatory activity in CON (n = 15), DAT (n = 8) and TH (n = 8) female mice. J RER in CON (n = 15), DAT (n = 8) and TH (n = 8) female mice. Differences between the groups were determined by one-way ANOVA and Tukey’s test for multiple comparisons (* P < 0.05, CON versus TH; # P < 0.05, DAT versus TH).